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Combating Illicit Xylazine Act
4/21/2026, 5:24 PM
Summary of Bill S 545
The bill prohibits the use of xylazine for non-medical purposes, such as recreational drug use or as an adulterant in illicit substances. It also imposes penalties for those found in violation of the prohibition, including fines and potential imprisonment.
The legislation is intended to address the growing concern over the misuse of xylazine and its potential dangers to public health. Supporters of the bill argue that restricting access to xylazine for non-medical purposes will help prevent overdoses and other negative health outcomes associated with its misuse. Opponents of the bill may argue that it could limit access to xylazine for legitimate medical purposes, potentially impacting veterinary care. However, the bill includes provisions to ensure that xylazine remains available for veterinary use under appropriate circumstances. Overall, Bill 119 s 545 seeks to strike a balance between addressing the misuse of xylazine and ensuring that it remains available for necessary medical purposes. It reflects a growing recognition of the need to address the misuse of certain substances and protect public health.
Congressional Summary of S 545
Combating Illicit Xylazine Act
This bill regulates xylazine under the Controlled Substances Act (CSA).
Xylazine, also known as tranq, is a nonopioid sedative and pain reliever that is approved for use in animals. Recently, the Drug Enforcement Administration (DEA) has reported an increase in trafficking of fentanyl mixed with xylazine.
This bill adds xylazine, including its salts, isomers, and salts of isomers, to schedule III of the CSA. Schedule III controlled substances, including anabolic steroids, buprenorphine, and ketamine, have less potential for abuse than a schedule I or II substance, have a currently accepted medical use, and have low or moderate risk of dependence if abused.
Under the bill, manufacturing, distributing, or dispensing xylazine, or possessing with intent to manufacture, distribute, or dispense xylazine for illicit use is subject to criminal penalties under the CSA. The bill also requires xylazine transactions to be tracked in the drug reporting system maintained by the DEA.
The bill exempts from registration under the CSA persons and entities that possess xylazine (1) lawfully dispensed by a veterinarian or pharmacy and (2) for an animal or for use in certain animal-control or wildlife programs.
The bill also exempts xylazine manufacturers from the CSA's physical security requirements.
Finally, the bill requires the DEA, in coordination with the Department of Health and Human Services (HHS), to provide Congress with a report on how the agencies previously determined whether xylazine should be a controlled substance, including the full text of HHS's recommendations to the DEA for scheduling xylazine.
Read the Full Bill
Current Status of Bill S 545
Bipartisan Support of Bill S 545
Total Number of Sponsors
1Democrat Sponsors
1Republican Sponsors
0Unaffiliated Sponsors
0Total Number of Cosponsors
91Democrat Cosponsors
46Republican Cosponsors
44Unaffiliated Cosponsors
1Policy Area and Potential Impact of Bill S 545
Primary Policy Focus
Crime and Law EnforcementAlternate Title(s) of Bill S 545
Comments

David Schwartz
3 months ago
This bill bad for me. It make things worse. I no like it.

Yahir Upchurch
1 year ago
I think this bill is great! It's gonna make things better for everyone. Can't wait to see how it all turns out!

Makai Moon
1 year ago
So, like, what's the deal with this bill trying to ban xylazine? I mean, I use that stuff for my horses all the time, and now they wanna take it away? How am I supposed to take care of my animals without it? This is seriously messed up. Can someone explain why they're trying to do this? #confused #notcool





